Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.13087/3517
Title: An overview of liquid chromatographic methods for analyzing new generation anti-epileptic drugs
Authors: ALSaeedy, Mohammed
Hasan, Ahmed
Al-Adhreai, Arwa
Alrabie, Ali
Qaba, Hafsah
Mashrah, Abdulrahman
Öncu-Kaya, Elif Mine
Keywords: Anti-epileptic drugs
epilepsy
liquid chromatography
separation
Tandem Mass-Spectrometry
Fluorescent Polarization Immunoassay
Bioanalytical Method Development
Solid-Phase Microextraction
Process-Related Impurities
Ampa Receptor Antagonist
Partial-Onset Seizures
Rp-Hplc Method
Eslicarbazepine Acetate
Human Plasma
Issue Date: 2022
Publisher: Taylor & Francis Inc
Abstract: Pregabalin, Lacosamide, Rufinamide, Perampanel, Eslicarbazepine acetate, Brivaracetam, Cannabidiol, Stiripentol, Everolimus, Cenobamate, and Fenfluramine are drugs of the third generation of antiepileptic drugs registered by International Coalition of Medicine Regulatory Authorities between 2000 and 2021. There are 213 peer-reviewed papers on antiepileptic drug analysis in the literature over the last three decades (1990-2022) which were reviewed in this article to provide an extensive overview of liquid chromatography techniques used to determine antiepileptic drugs. These details were discussed on the basis of a matrix: additives that are used to prepare a dosage form, sample preparation technique, column, limits of detection and quantification, types of elution in chromatography (isocratic or gradient), and detector. This review article will provide vital information to the scientific community in order to identify the most appropriate approach for antiepileptic drug analysis and determination.
URI: https://doi.org/10.1080/10826076.2022.2134146
https://hdl.handle.net/20.500.13087/3517
ISSN: 1082-6076
1520-572X
Appears in Collections:Kimya Bölümü Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu

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