Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.13087/1461
Title: VOLTAMMETRIC DETERMINATION OF ESTRADIOL IN MILK AND PHARMACEUTICALS BASED ON FUMED-SILICA MODIFIED CARBON PASTE ELECTRODE
Authors: Özcan, Ali
Topçuoğulları, Duygu
Özcan, Ayça Atılır
Keywords: Akustik
Astronomi ve Astrofizik
Biyoloji Çeşitliliğinin Korunması
Biyoloji
Kimya, Analitik
Kimya, Uygulamalı
Kimya, İnorganik ve Nükleer
Kimya, Tıbbi
Kimya, Organik
Fizikokimya
Ekoloji
Entomoloji
Çevre Bilimleri
Balıkçılık
Genetik ve Kalıtım
Limnoloji
Deniz ve Tatlı Su Biyolojisi
Matematik
Mikroskopi
Mineraloji
Mantar Bilimi
Optik
Kuş Bilimi
Fizik, Uygulamalı
Fizik, Atomik ve Moleküler Kimya
Fizik, Katı Hal
Fizik, Akışkanlar ve Plazma
Fizik, Matematik
Fizik, Nükleer
Fizik, Partiküller ve Alanlar
Spektroskopi
İstatistik ve Olasılık
Termodinamik
Taşınım
Su Kaynakları
Zooloji
Farmakoloji ve Eczacılık
Toksikoloji
Issue Date: 2018
Abstract: In this study, modification of carbon paste electrode (CPE) with a nano-structured substance, fumed silica (FS), was investigated to develop a voltammetric method for the determination of an endocrine disrupting chemical, estradiol (EST). FS prominently increased the voltammetric response of CPE towards EST. The parameters that affect the volmametric performance of modified CPE were examined to find the optimal conditions. Modified electrode showed a linear response towards EST between the concentration values of 0.1 ?M and 15.0 ?M EST. Limit of detection value for the method developed was calculated as 0.023 ?M. Production reproducibility of the modified electrode was obtained as 3.6 %. The voltammetric behavior of EST was also examined in the presence of different substances to evaluate their interference effects. The modified electrode successfully discriminated the oxidation potential of EST in the presence of different substances. The determination of EST was tested in milk and pharmaceutical samples to evaluate the analytical performance of the method. The recovery analysis of EST in milk samples showed that the modified electrode can be used safely in these samples. The modified electrode also achieved the determination of EST in pharmaceutical samples.
URI: https://doi.org/10.18038/aubtda.430622
https://hdl.handle.net/20.500.13087/1461
https://search.trdizin.gov.tr/yayin/detay/326962
ISSN: 1302-3160
2667-4211
Appears in Collections:Kimya Mühendisliği Bölümü Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu

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